graphene quantum dot nanoparticles Search Results


86
Burkard Manufacturing Co Ltd graphene quantum dots
Graphene Quantum Dots, supplied by Burkard Manufacturing Co Ltd, used in various techniques. Bioz Stars score: 86/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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90
Verlag GmbH colloidal graphene quantum dots
Colloidal Graphene Quantum Dots, supplied by Verlag GmbH, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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90
Reagen LLC graphene quantum dots
Graphene Quantum Dots, supplied by Reagen LLC, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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90
BioResource International Inc bioresource-derived graphene quantum dots
Bioresource Derived Graphene Quantum Dots, supplied by BioResource International Inc, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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90
Pulead Technology Industry Co Ltd zno quantum dots modified rgo
Zno Quantum Dots Modified Rgo, supplied by Pulead Technology Industry Co Ltd, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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90
Angstron Materials Inc graphene quantum dots
Graphene Quantum Dots, supplied by Angstron Materials Inc, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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90
Graphene Square graphene quantum dots
Graphene Quantum Dots, supplied by Graphene Square, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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Nanjing XFNANO Materials Tech Co Ltd aminated graphene
SEM of rGO ( A ) and Au/Ag-rGO ( B ), TEM <t>of</t> <t>Au/Ag-rGO/Aminated-GQDs/Carboxyl-GQDs</t> ( C ).
Aminated Graphene, supplied by Nanjing XFNANO Materials Tech Co Ltd, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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NanoHybrids Inc sn (iv) porphyrin-biotin decorated nitrogen doped graphene quantum dots
SEM of rGO ( A ) and Au/Ag-rGO ( B ), TEM <t>of</t> <t>Au/Ag-rGO/Aminated-GQDs/Carboxyl-GQDs</t> ( C ).
Sn (Iv) Porphyrin Biotin Decorated Nitrogen Doped Graphene Quantum Dots, supplied by NanoHybrids Inc, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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90
Nanjing XFNANO Materials Tech Co Ltd graphene quantum dots (gqds, 6–9 diameter, 0.8–1.2 thickness)
( A ) TEM image of a tungsten disulfide (WS 2 ) nanosheet. ( B ) TEM image of <t>graphene</t> quantum dots-tungsten disulfide nanosheet composite film modified glassy carbon electrode <t>(GQDs-WS</t> 2 ). ( C ) TEM image of gold nanoparticles (AuNPs). ( D ) SEM image of AuNPs/GQDs-WS 2 nanocomposite.
Graphene Quantum Dots (Gqds, 6–9 Diameter, 0.8–1.2 Thickness), supplied by Nanjing XFNANO Materials Tech Co Ltd, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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90
NanoHybrids Inc graphene quantum dots (gqds)
a Folic acid targeting ligand decorated self-assembled liposomal nanohybrid loaded multimode imaging probes, viz., gold nanoparticles (AuNPs as radiocontrast for X-ray computed tomography and reactive oxygen species scavenger) and <t>graphene</t> quantum dots <t>(GQDs</t> as fluorescent contrast for near-infrared fluorescence imaging and photothermal agent). Designed functional liposomal nanohybrids demonstrating photothermal response/heat and the generation of reactive oxygen species (ROS, considered as the side product of photothermal therapy) under near-infrared (NIR) light exposure. b NIR light mediated cancer therapeutic representation with tumor-bearing mice model using engineered liposomal nanotheranostic agents and targeted imaging bimodality of breast cancer through X-ray computed tomography (X-ray CT) and in vivo imaging system (IVIS). Liposomal nanotheranostics treated cancer cells displaying the production of ROS (green emission represents the presence of ROS captured by DCFDA (2′,7′-dichlorofluorescin diacetate) dye staining) during NIR light exposure, scale bar = 20 µm.
Graphene Quantum Dots (Gqds), supplied by NanoHybrids Inc, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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BioMimetic Therapeutics structural graphene quantum dots/mxene photothermal supercapacitor
Electrochemical performance of the biomimetic structural GQDs/MXene <t>photothermal</t> SCs. CV profiles of the GQDs/MXene‐720° SC at different scan rates a) in the dark and b) under 1 solar illumination. c) Comparative CV curves at 10 mV s −1 of the device in the dark and under 1 solar illumination. d) GCD curves of the SC at various current densities in the dark and under 1 solar illumination. e) Rate capability and f) Nyquist plots of the device in the dark and under 1 solar illumination. g) Ragone plot of the biomimetic structural GQDs/MXene photothermal SC in comparison with other recently reported 3D‐printed or MXene‐based SCs. h) Cycling performance of the device at 0.2 A cm −2 in the dark and under 1 solar illumination.
Structural Graphene Quantum Dots/Mxene Photothermal Supercapacitor, supplied by BioMimetic Therapeutics, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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Image Search Results


SEM of rGO ( A ) and Au/Ag-rGO ( B ), TEM of Au/Ag-rGO/Aminated-GQDs/Carboxyl-GQDs ( C ).

Journal: Scientific Reports

Article Title: Label-free Electrochemiluminescent Immunosensor for Detection of Prostate Specific Antigen based on Aminated Graphene Quantum Dots and Carboxyl Graphene Quantum Dots

doi: 10.1038/srep20511

Figure Lengend Snippet: SEM of rGO ( A ) and Au/Ag-rGO ( B ), TEM of Au/Ag-rGO/Aminated-GQDs/Carboxyl-GQDs ( C ).

Article Snippet: Aminated graphene, aminated graphene quantum dots and carboxyl graphene quantum dots were purchased from Nanjing XFNANO Materials Tech Co., Ltd. (China).

Techniques:

EIS in the presence of 5.0 mmol/L [Fe(CN) 6 ] 3−/4− solution containing 0.1 mol/L KCl ( A ) and ECL intensity–potential curves in PBS containing 100 mmol/L K 2 S 2 O 8 with the potential range of −2.0 to 0 V ( B ). (a) bare GCE (b) Au/Ag-rGO/Aminated-GQDs/Carboxyl-GQDs/GCE ( c ) PSA antibody/Au/Ag-rGO/Aminated-GQDs/Carboxyl-GQDs/GCE (d) BSA/PSA/Au/Ag-rGO/Aminated-GQDs/Carboxyl-GQDs/GCE (e) PSA/BSA/PSA antibody /Au/Ag-rGO/Aminated-GQDs/Carboxyl-GQDs/GCE.

Journal: Scientific Reports

Article Title: Label-free Electrochemiluminescent Immunosensor for Detection of Prostate Specific Antigen based on Aminated Graphene Quantum Dots and Carboxyl Graphene Quantum Dots

doi: 10.1038/srep20511

Figure Lengend Snippet: EIS in the presence of 5.0 mmol/L [Fe(CN) 6 ] 3−/4− solution containing 0.1 mol/L KCl ( A ) and ECL intensity–potential curves in PBS containing 100 mmol/L K 2 S 2 O 8 with the potential range of −2.0 to 0 V ( B ). (a) bare GCE (b) Au/Ag-rGO/Aminated-GQDs/Carboxyl-GQDs/GCE ( c ) PSA antibody/Au/Ag-rGO/Aminated-GQDs/Carboxyl-GQDs/GCE (d) BSA/PSA/Au/Ag-rGO/Aminated-GQDs/Carboxyl-GQDs/GCE (e) PSA/BSA/PSA antibody /Au/Ag-rGO/Aminated-GQDs/Carboxyl-GQDs/GCE.

Article Snippet: Aminated graphene, aminated graphene quantum dots and carboxyl graphene quantum dots were purchased from Nanjing XFNANO Materials Tech Co., Ltd. (China).

Techniques:

ECL intensity–potential curves ( A ), effect of pH ( B ) and the concentration of K 2 S 2 O 8 ( C ) on the ECL intensity. (a) bare GCE (b) Aminated-GQDs (2.5 mg/mL)/GCE (c) Carboxyl-GQDs (2.5 mg/mL)/GCE (d) Aminated-GQDs (2.5 mg/mL)/Carboxyl-GQDs (2.5 mg/mL)/GCE.

Journal: Scientific Reports

Article Title: Label-free Electrochemiluminescent Immunosensor for Detection of Prostate Specific Antigen based on Aminated Graphene Quantum Dots and Carboxyl Graphene Quantum Dots

doi: 10.1038/srep20511

Figure Lengend Snippet: ECL intensity–potential curves ( A ), effect of pH ( B ) and the concentration of K 2 S 2 O 8 ( C ) on the ECL intensity. (a) bare GCE (b) Aminated-GQDs (2.5 mg/mL)/GCE (c) Carboxyl-GQDs (2.5 mg/mL)/GCE (d) Aminated-GQDs (2.5 mg/mL)/Carboxyl-GQDs (2.5 mg/mL)/GCE.

Article Snippet: Aminated graphene, aminated graphene quantum dots and carboxyl graphene quantum dots were purchased from Nanjing XFNANO Materials Tech Co., Ltd. (China).

Techniques: Concentration Assay

( A ) TEM image of a tungsten disulfide (WS 2 ) nanosheet. ( B ) TEM image of graphene quantum dots-tungsten disulfide nanosheet composite film modified glassy carbon electrode (GQDs-WS 2 ). ( C ) TEM image of gold nanoparticles (AuNPs). ( D ) SEM image of AuNPs/GQDs-WS 2 nanocomposite.

Journal: Nanomaterials

Article Title: Label-Free Electrochemical Aptasensor for Sensitive Detection of Malachite Green Based on Au Nanoparticle/Graphene Quantum Dots/Tungsten Disulfide Nanocomposites

doi: 10.3390/nano9020229

Figure Lengend Snippet: ( A ) TEM image of a tungsten disulfide (WS 2 ) nanosheet. ( B ) TEM image of graphene quantum dots-tungsten disulfide nanosheet composite film modified glassy carbon electrode (GQDs-WS 2 ). ( C ) TEM image of gold nanoparticles (AuNPs). ( D ) SEM image of AuNPs/GQDs-WS 2 nanocomposite.

Article Snippet: Graphene quantum dots (GQDs, 6–9 nm diameter, 0.8–1.2 nm thickness) and tungsten disulfide nanosheets (WS 2 , 20–500 nm diameter, 1–8 nm thickness) were obtained from Nanjing XFNANO Materials Tech Co. Ltd. (Nanjing, China).

Techniques: Modification

Cyclic voltammetry responses of the bare glassy carbon electrode (GCE) ( a ), WS 2 /GCE ( b ), GQDs-WS 2 /GCE (c), and AuNPs/GQDs-WS 2 /GCE ( d ) towards 0.5 mM MG in pH 7.4 phosphate buffer. Scan rate: 100 mV s −1 .

Journal: Nanomaterials

Article Title: Label-Free Electrochemical Aptasensor for Sensitive Detection of Malachite Green Based on Au Nanoparticle/Graphene Quantum Dots/Tungsten Disulfide Nanocomposites

doi: 10.3390/nano9020229

Figure Lengend Snippet: Cyclic voltammetry responses of the bare glassy carbon electrode (GCE) ( a ), WS 2 /GCE ( b ), GQDs-WS 2 /GCE (c), and AuNPs/GQDs-WS 2 /GCE ( d ) towards 0.5 mM MG in pH 7.4 phosphate buffer. Scan rate: 100 mV s −1 .

Article Snippet: Graphene quantum dots (GQDs, 6–9 nm diameter, 0.8–1.2 nm thickness) and tungsten disulfide nanosheets (WS 2 , 20–500 nm diameter, 1–8 nm thickness) were obtained from Nanjing XFNANO Materials Tech Co. Ltd. (Nanjing, China).

Techniques:

( A ) Electrochemical impedance spectroscopy (EIS) spectra of the designed aptasensor at different modification stage. ( B ) CV responses of different modified electrode. ( a ) bare GCE, ( b ) AuNPs/GQDs-WS 2 /GCE, ( c ) aptamer/AuNPs/GQDs-WS 2 /GCE, ( d ) MCH/aptamer/AuNPs/GQDs-WS 2 /GCE, and ( e ) MG/MCH/aptamer/AuNPs/GQDs-WS 2 /GCE. The CV measurements were performed in 0.1M KCl solution containing 5 mM K 3 [Fe(CN) 6 ] at a scan rate of 50 mV s −1 .

Journal: Nanomaterials

Article Title: Label-Free Electrochemical Aptasensor for Sensitive Detection of Malachite Green Based on Au Nanoparticle/Graphene Quantum Dots/Tungsten Disulfide Nanocomposites

doi: 10.3390/nano9020229

Figure Lengend Snippet: ( A ) Electrochemical impedance spectroscopy (EIS) spectra of the designed aptasensor at different modification stage. ( B ) CV responses of different modified electrode. ( a ) bare GCE, ( b ) AuNPs/GQDs-WS 2 /GCE, ( c ) aptamer/AuNPs/GQDs-WS 2 /GCE, ( d ) MCH/aptamer/AuNPs/GQDs-WS 2 /GCE, and ( e ) MG/MCH/aptamer/AuNPs/GQDs-WS 2 /GCE. The CV measurements were performed in 0.1M KCl solution containing 5 mM K 3 [Fe(CN) 6 ] at a scan rate of 50 mV s −1 .

Article Snippet: Graphene quantum dots (GQDs, 6–9 nm diameter, 0.8–1.2 nm thickness) and tungsten disulfide nanosheets (WS 2 , 20–500 nm diameter, 1–8 nm thickness) were obtained from Nanjing XFNANO Materials Tech Co. Ltd. (Nanjing, China).

Techniques: Impedance Spectroscopy, Modification

CV responses of the aptasensor toward blank control ( a ), 1.0 μM MG ( c ), and 10 μM MG (d). Curve b shows the CV response of the AuNPs/GQDs-WS 2 /GCE toward 1.0 μM MG in pH 7.4 phosphate buffer. Scan rate: 100 mV s −1 .

Journal: Nanomaterials

Article Title: Label-Free Electrochemical Aptasensor for Sensitive Detection of Malachite Green Based on Au Nanoparticle/Graphene Quantum Dots/Tungsten Disulfide Nanocomposites

doi: 10.3390/nano9020229

Figure Lengend Snippet: CV responses of the aptasensor toward blank control ( a ), 1.0 μM MG ( c ), and 10 μM MG (d). Curve b shows the CV response of the AuNPs/GQDs-WS 2 /GCE toward 1.0 μM MG in pH 7.4 phosphate buffer. Scan rate: 100 mV s −1 .

Article Snippet: Graphene quantum dots (GQDs, 6–9 nm diameter, 0.8–1.2 nm thickness) and tungsten disulfide nanosheets (WS 2 , 20–500 nm diameter, 1–8 nm thickness) were obtained from Nanjing XFNANO Materials Tech Co. Ltd. (Nanjing, China).

Techniques: Control

a Folic acid targeting ligand decorated self-assembled liposomal nanohybrid loaded multimode imaging probes, viz., gold nanoparticles (AuNPs as radiocontrast for X-ray computed tomography and reactive oxygen species scavenger) and graphene quantum dots (GQDs as fluorescent contrast for near-infrared fluorescence imaging and photothermal agent). Designed functional liposomal nanohybrids demonstrating photothermal response/heat and the generation of reactive oxygen species (ROS, considered as the side product of photothermal therapy) under near-infrared (NIR) light exposure. b NIR light mediated cancer therapeutic representation with tumor-bearing mice model using engineered liposomal nanotheranostic agents and targeted imaging bimodality of breast cancer through X-ray computed tomography (X-ray CT) and in vivo imaging system (IVIS). Liposomal nanotheranostics treated cancer cells displaying the production of ROS (green emission represents the presence of ROS captured by DCFDA (2′,7′-dichlorofluorescin diacetate) dye staining) during NIR light exposure, scale bar = 20 µm.

Journal: Communications Biology

Article Title: Liposomal nanotheranostics for multimode targeted in vivo bioimaging and near‐infrared light mediated cancer therapy

doi: 10.1038/s42003-020-1016-z

Figure Lengend Snippet: a Folic acid targeting ligand decorated self-assembled liposomal nanohybrid loaded multimode imaging probes, viz., gold nanoparticles (AuNPs as radiocontrast for X-ray computed tomography and reactive oxygen species scavenger) and graphene quantum dots (GQDs as fluorescent contrast for near-infrared fluorescence imaging and photothermal agent). Designed functional liposomal nanohybrids demonstrating photothermal response/heat and the generation of reactive oxygen species (ROS, considered as the side product of photothermal therapy) under near-infrared (NIR) light exposure. b NIR light mediated cancer therapeutic representation with tumor-bearing mice model using engineered liposomal nanotheranostic agents and targeted imaging bimodality of breast cancer through X-ray computed tomography (X-ray CT) and in vivo imaging system (IVIS). Liposomal nanotheranostics treated cancer cells displaying the production of ROS (green emission represents the presence of ROS captured by DCFDA (2′,7′-dichlorofluorescin diacetate) dye staining) during NIR light exposure, scale bar = 20 µm.

Article Snippet: Fig. 2 Transmission electron microscopic (TEM) images of engineered liposomal nanotheranostics showing spherical morphology. a , b TEM images showing the successful encapsulation of graphene quantum dots (GQDs) in liposomal cavity, scale bar = 100 nm and 10 nm. c TEM imaging observation of gold nanoparticles (AuNPs) and graphene quantum dots (GQDs) encapsulated with liposomal nanohybrids named as NFGL, scale bar = 500 nm. d Selected area electron diffraction (SAED) pattern of NFGL nanohybrids, scale bar = 100 nm. e Microscopic image showing the distribution of parent liposomes (loaded with AuNPs and GQDs) with maintained spherical morphology, scale bar = 200 nm.

Techniques: Imaging, Computed Tomography, Fluorescence, Functional Assay, In Vivo Imaging, Staining

a , b TEM images showing the successful encapsulation of graphene quantum dots (GQDs) in liposomal cavity, scale bar = 100 nm and 10 nm. c TEM imaging observation of gold nanoparticles (AuNPs) and graphene quantum dots (GQDs) encapsulated with liposomal nanohybrids named as NFGL, scale bar = 500 nm. d Selected area electron diffraction (SAED) pattern of NFGL nanohybrids, scale bar = 100 nm. e Microscopic image showing the distribution of parent liposomes (loaded with AuNPs and GQDs) with maintained spherical morphology, scale bar = 200 nm.

Journal: Communications Biology

Article Title: Liposomal nanotheranostics for multimode targeted in vivo bioimaging and near‐infrared light mediated cancer therapy

doi: 10.1038/s42003-020-1016-z

Figure Lengend Snippet: a , b TEM images showing the successful encapsulation of graphene quantum dots (GQDs) in liposomal cavity, scale bar = 100 nm and 10 nm. c TEM imaging observation of gold nanoparticles (AuNPs) and graphene quantum dots (GQDs) encapsulated with liposomal nanohybrids named as NFGL, scale bar = 500 nm. d Selected area electron diffraction (SAED) pattern of NFGL nanohybrids, scale bar = 100 nm. e Microscopic image showing the distribution of parent liposomes (loaded with AuNPs and GQDs) with maintained spherical morphology, scale bar = 200 nm.

Article Snippet: Fig. 2 Transmission electron microscopic (TEM) images of engineered liposomal nanotheranostics showing spherical morphology. a , b TEM images showing the successful encapsulation of graphene quantum dots (GQDs) in liposomal cavity, scale bar = 100 nm and 10 nm. c TEM imaging observation of gold nanoparticles (AuNPs) and graphene quantum dots (GQDs) encapsulated with liposomal nanohybrids named as NFGL, scale bar = 500 nm. d Selected area electron diffraction (SAED) pattern of NFGL nanohybrids, scale bar = 100 nm. e Microscopic image showing the distribution of parent liposomes (loaded with AuNPs and GQDs) with maintained spherical morphology, scale bar = 200 nm.

Techniques: Encapsulation, Imaging, Liposomes

a Absorption spectra of parent liposome (loaded with AuNPs and GQDs), prepared graphene quantum dots (GQDs), and gold nanoparticles (AuNPs) and graphene quantum dots (GQDs) loaded liposomal nanohybrids named as NFGL at two different time points, viz., 0.5 h and 24 h, indicating the presence of multimode probes (GQDs and AuNPs) within liposomal particles. b Photoluminescence spectra of prepared graphene quantum dots, GQDs encapsulated liposomes, and engineered NFGL nanohybrids using 500 nm excitation wavelength, demonstrating better emissive property of fabricated nanotheranostics.

Journal: Communications Biology

Article Title: Liposomal nanotheranostics for multimode targeted in vivo bioimaging and near‐infrared light mediated cancer therapy

doi: 10.1038/s42003-020-1016-z

Figure Lengend Snippet: a Absorption spectra of parent liposome (loaded with AuNPs and GQDs), prepared graphene quantum dots (GQDs), and gold nanoparticles (AuNPs) and graphene quantum dots (GQDs) loaded liposomal nanohybrids named as NFGL at two different time points, viz., 0.5 h and 24 h, indicating the presence of multimode probes (GQDs and AuNPs) within liposomal particles. b Photoluminescence spectra of prepared graphene quantum dots, GQDs encapsulated liposomes, and engineered NFGL nanohybrids using 500 nm excitation wavelength, demonstrating better emissive property of fabricated nanotheranostics.

Article Snippet: Fig. 2 Transmission electron microscopic (TEM) images of engineered liposomal nanotheranostics showing spherical morphology. a , b TEM images showing the successful encapsulation of graphene quantum dots (GQDs) in liposomal cavity, scale bar = 100 nm and 10 nm. c TEM imaging observation of gold nanoparticles (AuNPs) and graphene quantum dots (GQDs) encapsulated with liposomal nanohybrids named as NFGL, scale bar = 500 nm. d Selected area electron diffraction (SAED) pattern of NFGL nanohybrids, scale bar = 100 nm. e Microscopic image showing the distribution of parent liposomes (loaded with AuNPs and GQDs) with maintained spherical morphology, scale bar = 200 nm.

Techniques: Liposomes

Elemental composition of gold nanoparticles (AuNPs) and graphene quantum dots (GQDs) encapsulated with liposomal nanohybrids (NFGL) analyzed through transmission electron microscopic (TEM) images showing the presence of nitrogen (N in maroon color), phosphorous (P in blue color), gold (Au in emerald color), and oxygen (O in pink color) elements with individual and merged imaging, scale bar = 300 nm.

Journal: Communications Biology

Article Title: Liposomal nanotheranostics for multimode targeted in vivo bioimaging and near‐infrared light mediated cancer therapy

doi: 10.1038/s42003-020-1016-z

Figure Lengend Snippet: Elemental composition of gold nanoparticles (AuNPs) and graphene quantum dots (GQDs) encapsulated with liposomal nanohybrids (NFGL) analyzed through transmission electron microscopic (TEM) images showing the presence of nitrogen (N in maroon color), phosphorous (P in blue color), gold (Au in emerald color), and oxygen (O in pink color) elements with individual and merged imaging, scale bar = 300 nm.

Article Snippet: Fig. 2 Transmission electron microscopic (TEM) images of engineered liposomal nanotheranostics showing spherical morphology. a , b TEM images showing the successful encapsulation of graphene quantum dots (GQDs) in liposomal cavity, scale bar = 100 nm and 10 nm. c TEM imaging observation of gold nanoparticles (AuNPs) and graphene quantum dots (GQDs) encapsulated with liposomal nanohybrids named as NFGL, scale bar = 500 nm. d Selected area electron diffraction (SAED) pattern of NFGL nanohybrids, scale bar = 100 nm. e Microscopic image showing the distribution of parent liposomes (loaded with AuNPs and GQDs) with maintained spherical morphology, scale bar = 200 nm.

Techniques: Transmission Assay, Imaging

a Contrast measurements (also known as radiodensity) of designed gold nanoparticles (AuNPs) and graphene quantum dots (GQDs)-loaded liposomal nanohybrids named as NFGL at various concentrations (5–100 µg/mL) using a clinical TOSHIBA 64 CT clinical scanner with 5 mm slice thickness and 1 s rotation time compared with parent liposome (loaded with AuNPs and GQDs), revealing the presence of AuNPs (high electron coefficient and density) within the liposomal framework. b Emission performance of NFGL and compared with parent liposomes and PBS using the in vivo imaging system (IVIS) showing the better contrast ability for deep tissue penetration, and indicating the presence of GQDs within liposomal assembly. c Time-dependent photothermal transduction performance of NFGL nanohybrids at 0.5 mg/mL concentration using 750 nm of NIR light irradiation (1 W/cm 2 ) compared with parent liposome ( n = 3), ensuring the potential impact of phototriggered therapy. d Digital photographs showing dispersion of NFGL at ambient conditions, and during laser exposure after 1 h and 24 h of time periods.

Journal: Communications Biology

Article Title: Liposomal nanotheranostics for multimode targeted in vivo bioimaging and near‐infrared light mediated cancer therapy

doi: 10.1038/s42003-020-1016-z

Figure Lengend Snippet: a Contrast measurements (also known as radiodensity) of designed gold nanoparticles (AuNPs) and graphene quantum dots (GQDs)-loaded liposomal nanohybrids named as NFGL at various concentrations (5–100 µg/mL) using a clinical TOSHIBA 64 CT clinical scanner with 5 mm slice thickness and 1 s rotation time compared with parent liposome (loaded with AuNPs and GQDs), revealing the presence of AuNPs (high electron coefficient and density) within the liposomal framework. b Emission performance of NFGL and compared with parent liposomes and PBS using the in vivo imaging system (IVIS) showing the better contrast ability for deep tissue penetration, and indicating the presence of GQDs within liposomal assembly. c Time-dependent photothermal transduction performance of NFGL nanohybrids at 0.5 mg/mL concentration using 750 nm of NIR light irradiation (1 W/cm 2 ) compared with parent liposome ( n = 3), ensuring the potential impact of phototriggered therapy. d Digital photographs showing dispersion of NFGL at ambient conditions, and during laser exposure after 1 h and 24 h of time periods.

Article Snippet: Fig. 2 Transmission electron microscopic (TEM) images of engineered liposomal nanotheranostics showing spherical morphology. a , b TEM images showing the successful encapsulation of graphene quantum dots (GQDs) in liposomal cavity, scale bar = 100 nm and 10 nm. c TEM imaging observation of gold nanoparticles (AuNPs) and graphene quantum dots (GQDs) encapsulated with liposomal nanohybrids named as NFGL, scale bar = 500 nm. d Selected area electron diffraction (SAED) pattern of NFGL nanohybrids, scale bar = 100 nm. e Microscopic image showing the distribution of parent liposomes (loaded with AuNPs and GQDs) with maintained spherical morphology, scale bar = 200 nm.

Techniques: Liposomes, In Vivo Imaging, Transduction, Concentration Assay, Irradiation, Dispersion

a Cancer cell imaging and cellular uptake of folic acid functionalized NFGL nanotheranostic agents (NFGL–FA) with 4T1 breast cancer cell lines with and without NIR light exposure (750 nm, 1 W/cm 2 for 10 min of exposure), scale bar = 10 µm. b Observations of produced reactive oxygen species (ROS, as a side product of photothermal therapy) during NIR light irradiation using various formulations of NFGL nanohybrids treated with 4T1 cancer cell lines; green emissive ROS are noticed by (2′,7′-dichlorofluorescin diacetate, DCFDA) dye staining. c Quantitative analysis of produced ROS from nanohybrids treated with breast cancer cells with and without NIR light irradiation ( n = 3). d Percentage cell viability of NFGL nanohybrids before and after folic acid functionalization and its major components (GQDs and AuNPs) using 24 h MTT assay at different concentrations (0.1–1 mg/mL, n = 3).

Journal: Communications Biology

Article Title: Liposomal nanotheranostics for multimode targeted in vivo bioimaging and near‐infrared light mediated cancer therapy

doi: 10.1038/s42003-020-1016-z

Figure Lengend Snippet: a Cancer cell imaging and cellular uptake of folic acid functionalized NFGL nanotheranostic agents (NFGL–FA) with 4T1 breast cancer cell lines with and without NIR light exposure (750 nm, 1 W/cm 2 for 10 min of exposure), scale bar = 10 µm. b Observations of produced reactive oxygen species (ROS, as a side product of photothermal therapy) during NIR light irradiation using various formulations of NFGL nanohybrids treated with 4T1 cancer cell lines; green emissive ROS are noticed by (2′,7′-dichlorofluorescin diacetate, DCFDA) dye staining. c Quantitative analysis of produced ROS from nanohybrids treated with breast cancer cells with and without NIR light irradiation ( n = 3). d Percentage cell viability of NFGL nanohybrids before and after folic acid functionalization and its major components (GQDs and AuNPs) using 24 h MTT assay at different concentrations (0.1–1 mg/mL, n = 3).

Article Snippet: Fig. 2 Transmission electron microscopic (TEM) images of engineered liposomal nanotheranostics showing spherical morphology. a , b TEM images showing the successful encapsulation of graphene quantum dots (GQDs) in liposomal cavity, scale bar = 100 nm and 10 nm. c TEM imaging observation of gold nanoparticles (AuNPs) and graphene quantum dots (GQDs) encapsulated with liposomal nanohybrids named as NFGL, scale bar = 500 nm. d Selected area electron diffraction (SAED) pattern of NFGL nanohybrids, scale bar = 100 nm. e Microscopic image showing the distribution of parent liposomes (loaded with AuNPs and GQDs) with maintained spherical morphology, scale bar = 200 nm.

Techniques: Imaging, Produced, Irradiation, Staining, MTT Assay

a Planned NIR light mediated phototriggered strategy for post-injected 4T1 tumor bearing mice showing enhanced tumor uptake of injected gold nanoparticles (AuNPs) and graphene quantum dots (GQDs) loaded liposomal nanotheranostics with folic acid functionalization (NFGL–FA). b Experimental flowchart from day 0 (cell culture) to tissue collection (36 days) followed by multimodal tumor diagnosis and biodistribution experiment setup. c Localized tumor diagnosis and specific biodistribution measurements after 48 h of time before and after NIR light exposure (750 nm, 1 W/cm 2 for 10 min) followed by whole body X-ray computed tomography scans with coronal and axial CT slices of mice body using TOSHIBA 64 CT scanner at 120 kVp tube voltage and 250 mA tube current with 5 mm slice thickness and 1 s rotation time. d Targeted deep tumor localization in mice body before and after NIR light exposure (750 nm, 1 W/cm 2 for 10 min) using the in vivo imaging system (IVIS). In both imaging modalities, pre-injected mice were considered as control groups.

Journal: Communications Biology

Article Title: Liposomal nanotheranostics for multimode targeted in vivo bioimaging and near‐infrared light mediated cancer therapy

doi: 10.1038/s42003-020-1016-z

Figure Lengend Snippet: a Planned NIR light mediated phototriggered strategy for post-injected 4T1 tumor bearing mice showing enhanced tumor uptake of injected gold nanoparticles (AuNPs) and graphene quantum dots (GQDs) loaded liposomal nanotheranostics with folic acid functionalization (NFGL–FA). b Experimental flowchart from day 0 (cell culture) to tissue collection (36 days) followed by multimodal tumor diagnosis and biodistribution experiment setup. c Localized tumor diagnosis and specific biodistribution measurements after 48 h of time before and after NIR light exposure (750 nm, 1 W/cm 2 for 10 min) followed by whole body X-ray computed tomography scans with coronal and axial CT slices of mice body using TOSHIBA 64 CT scanner at 120 kVp tube voltage and 250 mA tube current with 5 mm slice thickness and 1 s rotation time. d Targeted deep tumor localization in mice body before and after NIR light exposure (750 nm, 1 W/cm 2 for 10 min) using the in vivo imaging system (IVIS). In both imaging modalities, pre-injected mice were considered as control groups.

Article Snippet: Fig. 2 Transmission electron microscopic (TEM) images of engineered liposomal nanotheranostics showing spherical morphology. a , b TEM images showing the successful encapsulation of graphene quantum dots (GQDs) in liposomal cavity, scale bar = 100 nm and 10 nm. c TEM imaging observation of gold nanoparticles (AuNPs) and graphene quantum dots (GQDs) encapsulated with liposomal nanohybrids named as NFGL, scale bar = 500 nm. d Selected area electron diffraction (SAED) pattern of NFGL nanohybrids, scale bar = 100 nm. e Microscopic image showing the distribution of parent liposomes (loaded with AuNPs and GQDs) with maintained spherical morphology, scale bar = 200 nm.

Techniques: Injection, Cell Culture, Biomarker Discovery, Computed Tomography, In Vivo Imaging, Imaging, Control

a Whole body in vivo imaging for site-selective 4T1 tumor diagnosis at various time points (1, 24, and 48 h) of intravenously injected gold nanoparticles (AuNPs) and graphene quantum dots (GQDs) loaded liposomal nanotheranostics with folic acid functionalization (NFGL–FA). b Ex vivo imaging of collected major organs and 4T1 tumor after 48 h from intravenously nanotheranostics injected animals. c Digital photographs of 4T1 tumor bearing mice during their therapeutic conditions after intravenous injection of NFGL–FA nanotheranostics (n = 3 mice per group) showing the successive tumor regression in various therapeutic conditions with good health of treated mice. d , e Measurements of tumor reduction by tumor volume (mm 3 , * p < 0.05) and tumor weight (gram, * p < 0.05, ** p < 0.01) analysis ( n = 3 mice per group) during various therapeutic conditions using different formulations of NFGL–FA nanotheranostics with and without NIR light exposure (750 nm, 1 W/cm 2 for 10 min), and compared with the control group of animals (pre-injected and untreated mice). f Digital photograph of collected tumors after various therapeutic assessments using different formulations of NFGL–FA nanotheranostics representing the promising tumor reduction and potential impact of phototriggered cancer therapy.

Journal: Communications Biology

Article Title: Liposomal nanotheranostics for multimode targeted in vivo bioimaging and near‐infrared light mediated cancer therapy

doi: 10.1038/s42003-020-1016-z

Figure Lengend Snippet: a Whole body in vivo imaging for site-selective 4T1 tumor diagnosis at various time points (1, 24, and 48 h) of intravenously injected gold nanoparticles (AuNPs) and graphene quantum dots (GQDs) loaded liposomal nanotheranostics with folic acid functionalization (NFGL–FA). b Ex vivo imaging of collected major organs and 4T1 tumor after 48 h from intravenously nanotheranostics injected animals. c Digital photographs of 4T1 tumor bearing mice during their therapeutic conditions after intravenous injection of NFGL–FA nanotheranostics (n = 3 mice per group) showing the successive tumor regression in various therapeutic conditions with good health of treated mice. d , e Measurements of tumor reduction by tumor volume (mm 3 , * p < 0.05) and tumor weight (gram, * p < 0.05, ** p < 0.01) analysis ( n = 3 mice per group) during various therapeutic conditions using different formulations of NFGL–FA nanotheranostics with and without NIR light exposure (750 nm, 1 W/cm 2 for 10 min), and compared with the control group of animals (pre-injected and untreated mice). f Digital photograph of collected tumors after various therapeutic assessments using different formulations of NFGL–FA nanotheranostics representing the promising tumor reduction and potential impact of phototriggered cancer therapy.

Article Snippet: Fig. 2 Transmission electron microscopic (TEM) images of engineered liposomal nanotheranostics showing spherical morphology. a , b TEM images showing the successful encapsulation of graphene quantum dots (GQDs) in liposomal cavity, scale bar = 100 nm and 10 nm. c TEM imaging observation of gold nanoparticles (AuNPs) and graphene quantum dots (GQDs) encapsulated with liposomal nanohybrids named as NFGL, scale bar = 500 nm. d Selected area electron diffraction (SAED) pattern of NFGL nanohybrids, scale bar = 100 nm. e Microscopic image showing the distribution of parent liposomes (loaded with AuNPs and GQDs) with maintained spherical morphology, scale bar = 200 nm.

Techniques: In Vivo Imaging, Biomarker Discovery, Injection, Ex Vivo, Imaging, Control

a Percentage of hemolysis efficacy of liposomes, gold nanoparticles (AuNPs), and graphene quantum dots (GQDs) loaded liposomal nanotheranostics (NFGL) before and after FA attachment at various concentrations (10–200 µg/mL, n = 3). b Body weight measurements of post-injected various mice groups ( n = 3). Both the analysis demonstrate the good biocompatibility and safety of engineered liposomal nanotheranostic agents.

Journal: Communications Biology

Article Title: Liposomal nanotheranostics for multimode targeted in vivo bioimaging and near‐infrared light mediated cancer therapy

doi: 10.1038/s42003-020-1016-z

Figure Lengend Snippet: a Percentage of hemolysis efficacy of liposomes, gold nanoparticles (AuNPs), and graphene quantum dots (GQDs) loaded liposomal nanotheranostics (NFGL) before and after FA attachment at various concentrations (10–200 µg/mL, n = 3). b Body weight measurements of post-injected various mice groups ( n = 3). Both the analysis demonstrate the good biocompatibility and safety of engineered liposomal nanotheranostic agents.

Article Snippet: Fig. 2 Transmission electron microscopic (TEM) images of engineered liposomal nanotheranostics showing spherical morphology. a , b TEM images showing the successful encapsulation of graphene quantum dots (GQDs) in liposomal cavity, scale bar = 100 nm and 10 nm. c TEM imaging observation of gold nanoparticles (AuNPs) and graphene quantum dots (GQDs) encapsulated with liposomal nanohybrids named as NFGL, scale bar = 500 nm. d Selected area electron diffraction (SAED) pattern of NFGL nanohybrids, scale bar = 100 nm. e Microscopic image showing the distribution of parent liposomes (loaded with AuNPs and GQDs) with maintained spherical morphology, scale bar = 200 nm.

Techniques: Liposomes, Injection

Electrochemical performance of the biomimetic structural GQDs/MXene photothermal SCs. CV profiles of the GQDs/MXene‐720° SC at different scan rates a) in the dark and b) under 1 solar illumination. c) Comparative CV curves at 10 mV s −1 of the device in the dark and under 1 solar illumination. d) GCD curves of the SC at various current densities in the dark and under 1 solar illumination. e) Rate capability and f) Nyquist plots of the device in the dark and under 1 solar illumination. g) Ragone plot of the biomimetic structural GQDs/MXene photothermal SC in comparison with other recently reported 3D‐printed or MXene‐based SCs. h) Cycling performance of the device at 0.2 A cm −2 in the dark and under 1 solar illumination.

Journal: Advanced Science

Article Title: Nature‐Inspired 3D Spiral Grass Structured Graphene Quantum Dots/MXene Nanohybrids with Exceptional Photothermal‐Driven Pseudo‐Capacitance Improvement

doi: 10.1002/advs.202204086

Figure Lengend Snippet: Electrochemical performance of the biomimetic structural GQDs/MXene photothermal SCs. CV profiles of the GQDs/MXene‐720° SC at different scan rates a) in the dark and b) under 1 solar illumination. c) Comparative CV curves at 10 mV s −1 of the device in the dark and under 1 solar illumination. d) GCD curves of the SC at various current densities in the dark and under 1 solar illumination. e) Rate capability and f) Nyquist plots of the device in the dark and under 1 solar illumination. g) Ragone plot of the biomimetic structural GQDs/MXene photothermal SC in comparison with other recently reported 3D‐printed or MXene‐based SCs. h) Cycling performance of the device at 0.2 A cm −2 in the dark and under 1 solar illumination.

Article Snippet: A biomimetic structural graphene quantum dots/MXene photothermal supercapacitor inspired by the light‐trapping effect of wide‐leaf spiral grass is developed.

Techniques: Comparison

Electrochemical performance of the biomimetic structural GQDs/MXene‐720° photothermal SC under sunlight with different power densities. a) Surface temperature, b) CV curves at 100 mV s −1 , c) GCD curves at 100 mA cm −2 , and d) Nyquist plots of the symmetric GQDs/MXene‐720° SC under solar illumination at different power densities. e) Schematic illustration of the structure‐enhanced solar thermal‐driven capacitance enhancement of the biomimetic structural GQDs/MXene photothermal SC.

Journal: Advanced Science

Article Title: Nature‐Inspired 3D Spiral Grass Structured Graphene Quantum Dots/MXene Nanohybrids with Exceptional Photothermal‐Driven Pseudo‐Capacitance Improvement

doi: 10.1002/advs.202204086

Figure Lengend Snippet: Electrochemical performance of the biomimetic structural GQDs/MXene‐720° photothermal SC under sunlight with different power densities. a) Surface temperature, b) CV curves at 100 mV s −1 , c) GCD curves at 100 mA cm −2 , and d) Nyquist plots of the symmetric GQDs/MXene‐720° SC under solar illumination at different power densities. e) Schematic illustration of the structure‐enhanced solar thermal‐driven capacitance enhancement of the biomimetic structural GQDs/MXene photothermal SC.

Article Snippet: A biomimetic structural graphene quantum dots/MXene photothermal supercapacitor inspired by the light‐trapping effect of wide‐leaf spiral grass is developed.

Techniques: